HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(Pyrimidin-2-yloxy)acetic acid → N-{[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}-2-(pyrimidin-2-yloxy)acetamide monohydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(Pyrimidin-2-yloxy)acetic acid | HCID 566272 | — |
| Edukt | tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate | HCID 66975002 | — |
| Produkt | N-{[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}-2-(pyrimidin-2-yloxy)acetamide monohydrochloride | HCID 66975597 | — |
Reaktionsschritte
Using tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate and (pyrimidin-2-yloxy)acetic acid, and by a method similar to that of Example 39, the title compound was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08722662B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-4b03d794624543998b1726c3575c786a |
| Quellennotiz | uspto-grants-2014_05 |