2-((Pyridin-2-yl)formamido)acetic acid → N-[2-({[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}amino)-2-oxoethyl]pyridine-2-carboxamide monohydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-((Pyridin-2-yl)formamido)acetic acid	HCID 11788622	—
Edukt	tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate	HCID 66975002	—
Produkt	N-[2-({[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}amino)-2-oxoethyl]pyridine-2-carboxamide monohydrochloride	HCID 66976410	—

Reaktionsschritte

Using tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate and N-(pyridin-2-ylcarbonyl)glycine, and by a method similar to that of Example 39, the title compound was obtained.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08722662B2
Quelldatensatz	uspto-grants-2014_05
ORD ID	ord-69bcf54c1e344bfba0235ce7c5fede1c
Quellennotiz	uspto-grants-2014_05