HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(N-methyl-1-pyridin-2-ylformamido)acetic acid → N-[2-({[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}amino)-2-oxoethyl]-N-methylpyridine-2-carboxamide monohydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(N-methyl-1-pyridin-2-ylformamido)acetic acid | HCID 16776132 | — |
| Edukt | tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate | HCID 66975002 | — |
| Produkt | N-[2-({[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}amino)-2-oxoethyl]-N-methylpyridine-2-carboxamide monohydrochloride | HCID 66976522 | — |
Reaktionsschritte
Using tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate and N-methyl-N-(pyridin-2-ylcarbonyl)glycine, and by a method similar to that of Example 39, the title compound was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08722662B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-a3e4168c47bb4b72bcbde8de7c6bb3f4 |
| Quellennotiz | uspto-grants-2014_05 |