HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-acetylanthranilic acid → 3-{[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}-2-methylquinazolin-4(3H)-one monohydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-acetylanthranilic acid | HCID 6971 | — |
| Edukt | tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate | HCID 66975002 | — |
| Produkt | 3-{[(6S,7R)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepan-6-yl]methyl}-2-methylquinazolin-4(3H)-one monohydrochloride | HCID 66976700 | — |
Reaktionsschritte
Using tert-butyl (6R,7R)-6-(aminomethyl)-7-(4-chloro-3-fluorophenyl)-1,4-oxazepane-4-carboxylate and 2-(acetylamino)benzoic acid, and by a method similar to that of Example 39, the title compound was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08722662B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-752753948b8e49edab6ff8b64c1b4bbd |
| Quellennotiz | uspto-grants-2014_05 |