1,2,4-Triazole-1-acetic acid → N-{[(6RS,7SR)-6-(3,4-dichlorophenyl)-1,4-oxazepan-7-yl]methyl}-2-(1H-1,2,4-triazol-1-yl)acetamide monohydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1,2,4-Triazole-1-acetic acid	HCID 1810180	—
Edukt	tert-butyl (6RS,7SR)-7-(aminomethyl)-6-(3,4-dichlorophenyl)-1,4-oxazepane-4-carboxylate	HCID 66975190	—
Produkt	N-{[(6RS,7SR)-6-(3,4-dichlorophenyl)-1,4-oxazepan-7-yl]methyl}-2-(1H-1,2,4-triazol-1-yl)acetamide monohydrochloride	HCID 66975689	—

Reaktionsschritte

Using tert-butyl (6RS,7SR)-7-(aminomethyl)-6-(3,4-dichlorophenyl)-1,4-oxazepane-4-carboxylate and 2-(1H-1,2,4-triazol-1-yl)acetic acid, and by a method similar to that of Example 39, step A and Example 449, step B, the title compound was obtained.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08722662B2
Quelldatensatz	uspto-grants-2014_05
ORD ID	ord-711878dd5b7e48588d66498cd02cd52b
Quellennotiz	uspto-grants-2014_05