HCID 67235751, Verbindung → HCID 53241715, Verbindung
Reaktionsgleichung
CC(C1C=[C:6]([O:10]C2N=CC(NC(=O)[C@@H](C)N)=CC=2)C=CC=1)C.[CH3:23][C:24]1[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][C:25]=1[O:31][C:32]1[N:37]=[CH:36][C:35]([NH:38][C:39](=[O:43])[C@@H:40]([CH3:42])[NH2:41])=[CH:34][CH:33]=1>>[CH3:23][C:24]1[CH:29]=[CH:28][C:27]([CH3:30])=[CH:26][C:25]=1[O:31][C:32]1[N:37]=[CH:36][C:35]([N:38]2[C:39](=[O:43])[C@@H:40]([CH3:42])[NH:41][C:6]2=[O:10])=[CH:34][CH:33]=1Komponenten
3
Versuchsvorschrift
The title compound was made in a similar fashion to the preparation of Example 9 replacing N1-(6-{[3-(1-methylethyl)phenyl]oxy}-3-pyridinyl)-D-alaninamide with N1-{6-[(2,5-dimethylphenyl)oxy]-3-pyridinyl}-D-alaninamide (Intermediate 36, 48 mg) to afford the title compound as a yellow powder (31 mg).
Quellen und Nachweise
- ORD-Eintrag
- ord-d214eead9c7e451e97c63e2c4f7d471d
- Quelldatensatz
- uspto-grants-2014_05