HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isoxazolidine hydrochloride → 3-(4-Chloro-2-hydroxy-3-(isoxazolidin-2-ylsulfonyl)phenylamino)-4-ethoxycyclobut-3-ene-1,2-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isoxazolidine hydrochloride | HCID 12304500 | — |
| Edukt | Ethyl(methoxy)amine hydrochloride | HCID 22613948 | — |
| Edukt | 6-Chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-ethyl-benzenesulfonamide | HCID 86638631 | — |
| Produkt | 3-(4-Chloro-2-hydroxy-3-(isoxazolidin-2-ylsulfonyl)phenylamino)-4-ethoxycyclobut-3-ene-1,2-dione | HCID 86658404 | — |
Reaktionsschritte
This compound was prepared analogously to 6-chloro-3-(2-ethoxy-3,4-dioxo-cyclobut-1-enylamino)-2-hydroxy-N-methoxy-N-ethyl-benzenesulfonamide (Intermediate FA) by replacing N-ethyl-O-methylhydroxylamine hydrochloride (Intermediate G) with isoxazolidine hydrochloride. [M+H]+ 402.9
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08722925B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-e0f6396d7865471bbd0552441adfe1f6 |
| Quellennotiz | uspto-grants-2014_05 |