HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine → 5-bromo-6-(2,2,2-trifluoroethoxy)-N-((3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl)methyl)nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3-(Trifluoromethyl)-1,2,4-oxadiazol-5-YL)methanamine | HCID 55263061 | — |
| Edukt | 5-Bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid | HCID 58192592 | — |
| Produkt | 5-bromo-6-(2,2,2-trifluoroethoxy)-N-((3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl)methyl)nicotinamide | HCID 86663143 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 1 using 5-bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1211586-75-2) and 3-trifluoromethyl-[1,2,4]oxadiazol-5-methanamine (example AK) as starting materials; LC-MS (UV peak area/ESI) 97%, 448.9532 (M−H)−.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08729105B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-0ea2edd16e1d4789ac75c8d60c20e58b |
| Quellennotiz | uspto-grants-2014_05 |