HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Aminoindole → 3-Ethoxycarbonyl-7-(5-indolylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Aminoindole | HCID 78867 | — |
| Edukt | 7-Chloro-3-ethoxycarbonyl-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine | HCID 86646290 | — |
| Produkt | 3-Ethoxycarbonyl-7-(5-indolylamino)-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine | HCID 67540795 | 100,5% |
Reaktionsschritte
In the same manner as in Example 19, step 5 and using 7-chloro-3-ethoxycarbonyl-6-(4-phenylpiperidine-1-carbonyl)pyrazolo[1,5-a]pyrimidine (0.15 g, 0.36 mmol) obtained in Example 19, step 4 and 5-aminoindole (0.072 g, 0.54 mmol), the title compound (0.184 g, 99%) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08729264B2 |
| Quelldatensatz | uspto-grants-2014_05 |
| ORD ID | ord-1a4a0a7bd5214fd0891722e4493c3dfd |
| Quellennotiz | uspto-grants-2014_05 |