Benzamide, N-(3-aminophenyl)- → 1-(3-Benzamidophenylamino)-N-(2-(dimethylamino)ethyl)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-9-carboxamide

HRID 1029241

Reaktionsgleichung

Reaktionsgleichung von HRID 1029241
Cl[C:2]1[CH:11]=[CH:10][N:9]=[C:8]2[C:3]=1[C:4]1[CH:16]=[C:15]([C:17]([NH:19][CH2:20][CH2:21][N:22]([CH3:24])[CH3:23])=[O:18])[CH:14]=[CH:13][C:5]=1[C:6](=[O:12])[NH:7]2.[NH2:25][C:26]1[CH:27]=[C:28]([NH:32][C:33](=[O:40])[C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[CH:29]=[CH:30][CH:31]=1>>[C:33]([NH:32][C:28]1[CH:27]=[C:26]([NH:25][C:2]2[CH:11]=[CH:10][N:9]=[C:8]3[C:3]=2[C:4]2[CH:16]=[C:15]([C:17]([NH:19][CH2:20][CH2:21][N:22]([CH3:24])[CH3:23])=[O:18])[CH:14]=[CH:13][C:5]=2[C:6](=[O:12])[NH:7]3)[CH:31]=[CH:30][CH:29]=1)(=[O:40])[C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1

Komponenten

3

Edukt 2

HCID 72896Benzamide, N-(3-aminophenyl)-HCID 698106731-Chloro-N-(2-(dimethylamino)ethyl)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-9-carboxamide

Produkt 1

HCID 698116301-(3-Benzamidophenylamino)-N-(2-(dimethylamino)ethyl)-6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridine-9-carboxamide

Versuchsvorschrift

The title compound was synthesized according to the procedure described for the preparation of Example 267 using 296 (40 mg, 0.12 mmol) and N-(3-amino-phenyl)-benzamide to provide 301. LC-MS (M+H=521, obsd.=521).

Aufarbeitung

  1. customThe title compound was synthesized

Quellen und Nachweise

ORD-Eintrag
ord-e287c48075f84540a658f3b3ba548399
Quelldatensatz
uspto-grants-2014_05
Patentnummer
US08735584B2

Verknüpfte Notizen

Wird geladen…