Triethylamine → 4-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one

HRID 1029355

Reaktionsgleichung

Reaktionsgleichung von HRID 1029355
[CH3:1][C:2]1[NH:3][N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:7])[CH:6]=1.S(C1C=CC(C)=CC=1)([O-])(=O)=O.CS[C:27]1[S:28][C:29]2[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=2[N+:31]=1[CH3:32].C(N(CC)CC)C>CO>[CH3:32][N:31]1[C:30]2[CH:33]=[CH:34][CH:35]=[CH:36][C:29]=2[S:28](=[C:6]2[C:5](=[O:7])[N:4]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)[NH:3][CH:2]2[CH3:1])[CH2:27]1

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 41464Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1)HCID 703351H-Pyrazol-5-ol, 3-methyl-1-phenyl-

Produkt 1

HCID 867456114-[-3-Methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.68 g (0.01 mol) 2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for one hour, then filtered and washed with methanol. After drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000).

Aufarbeitung

  1. filtrationfiltered
  2. washwashed with methanol
  3. customAfter drying the yield was 2.46 g (78%), mp 159°-162° C., λmax=375 (ε=25,000)

Quellen und Nachweise

ORD-Eintrag
ord-6cbb14defca149e0998b6ab85d6dad14
Quelldatensatz
uspto-grants-1992_04
Patentnummer
US05102781

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