Triethylamine → 4-[5-Methoxy-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-on

HRID 1029358

Reaktionsgleichung

Reaktionsgleichung von HRID 1029358
[CH3:1][C:2]1[NH:3][N:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:5](=[O:7])[CH:6]=1.S(C1C=CC(C)=CC=1)([O-])(=O)=O.[CH3:25][O:26][C:27]1[CH:28]=[CH:29][C:30]2[S:34][C:33](SC)=[N+:32]([CH3:37])[C:31]=2[CH:38]=1.C(N(CC)CC)C>CO>[CH3:25][O:26][C:27]1[CH:28]=[CH:29][C:30]2[S:34](=[C:6]3[C:5](=[O:7])[N:4]([C:8]4[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=4)[NH:3][CH:2]3[CH3:1])[CH2:33][N:32]([CH3:37])[C:31]=2[CH:38]=1

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 703351H-Pyrazol-5-ol, 3-methyl-1-phenyl-HCID 867456125-Methoxy-2-methylthio-3-methylbenzothiazolium tosylate

Produkt 1

HCID 867456134-[5-Methoxy-3-methylbenzothiazolinylidene]-3-methyl-1-phenylpyrazolin-5-on

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

3-Methyl-1-phenylpyrazolin-5-one (1.74 g, 0.01 mol) was mixed with 3.97 g (0.01 mol) 5-methoxy-2-methylthio-3-methylbenzothiazolium tosylate in 25 ml methanol. Triethylamine (1.01 g, 0.01 mol) was added. The mixture was stirred for 3.5 hours, then filtered and washed with methanol. After drying the yield was 276 g (79%), mp 155°-156° C., λmax=386 (ε=25,000).

Aufarbeitung

  1. filtrationfiltered
  2. washwashed with methanol
  3. customAfter drying the yield was 276 g (79%), mp 155°-156° C., λmax=386 (ε=25,000)

Quellen und Nachweise

ORD-Eintrag
ord-5ddf10501a9142da9f7d5ad3f0804a4a
Quelldatensatz
uspto-grants-1992_04
Patentnummer
US05102781

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