2-(Bromomethyl)-4-fluoro-1-nitrobenzene → N-(5-fluoro-2-nitrophenyl)methyl-phthalimide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A solution of 5-fluoro-2-nitro-benzylbromide (6.2 g) in dimethylformamide (20 ml) was dropped into a stirred suspension of potassium phthalimide (4.9 g) in the same solvent (40 ml). The mixture was heated under stirring to 90° C. for 2 hours, then cooled and diluted with water. The title compound (7.2 g) was recovered by filtration. M.p. 198°-200° C.

Herkunft & Nachweise