HCID 14078470, Verbindung → 4-Methoxybenzaldehyde

HRID 1030703Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1030703
O[C:2]1[C:7](CC=C(C)C)=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][C:3]=1[C:15](=[O:17])C>C(O)C>[CH:15](=[O:17])[C:3]1[CH:2]=[CH:7][C:6]([O:13][CH3:14])=[CH:5][CH:4]=1

Komponenten

3

Edukt 1

HCID 14078470HCID 14078470, Verbindung

Produkt 1

HCID 312444-Methoxybenzaldehyde

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

In 5 ml of ethanol were dissolved 0.4 g of the 2'-hydroxy-4'-methoxy-3'-(3-methyl-2-butenyl)acetophenone obtained in Production Example 2 and 0.3 ml of p-anisaldehyde, and the solution was cooled to 0° C. and 7.5 ml of a saturated solution of potassium hydroxide in ethanol was added to the solution. In a nitrogen current, the mixture was stirred at 0° C. for 30 minutes and at room temperature for 4 days. After the reaction, hydrochloric acid was added to the reaction liquid under cooling and the reaction liquid was gradually made acidic, and the formed precipitate was recovered by filtration and recrystallized from methanol to obtain 0.4 g (yield=64.7%) of 2'-hydroxy-4,4'-dimethoxy3'-(3-methyl-2-butenyl)chalcone in the form of a yellow needle.

Quellen und Nachweise

ORD-Eintrag
ord-fb9a71f8818b4f179a593cac0cb31f70
Quelldatensatz
uspto-grants-1992_04
Patentnummer
US05106871

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