Acetyl chloride → N-Dodecylacetamide

HRID 1032282Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1032282
[CH2:1]([NH2:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(N(CC)CC)C.[C:21](Cl)(=[O:23])[CH3:22]>ClCCl>[C:21]([NH:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12])(=[O:23])[CH3:22]

Komponenten

5

Edukt 3

HCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 13583Dodecylamine

Produkt 1

HCID 19764N-Dodecylacetamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

A mixture of 1-dodecylamine (1.049 g, 5.59 mmol), triethylamine (0.86 ml, 6.15 mmol) and acetyl chloride (0.44 ml, 6.15 mmol) in dichloromethane (10 ml) was stirred at room temperature for 3h. The mixture was quenched with water and the organic phase was separated. Evaporation of the dried (magnesium sulfate) organic phase gave a solid, which was recrystallized from hexane to give the titled amide.

Aufarbeitung

  1. customThe mixture was quenched with water
  2. customthe organic phase was separated
  3. customEvaporation of the
  4. dry with materialdried (magnesium sulfate) organic phase
  5. customgave a solid, which
  6. customwas recrystallized from hexane

Quellen und Nachweise

ORD-Eintrag
ord-1c95227a49a044f4a215eed2c8de5bdb
Quelldatensatz
uspto-grants-1990_09
Patentnummer
US04957917

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