HCID 14722828, Verbindung → HCID 22399592, Verbindung

HRID 1033658Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1033658
[CH:1]1([CH2:4][C:5]2[C:6]([OH:15])=[C:7]([CH:11]=[CH:12][C:13]=2[OH:14])[C:8]([NH2:10])=[O:9])[CH2:3][CH2:2]1.I[CH2:17][CH2:18][CH2:19][O:20][C:21]1[CH:34]=[CH:33][C:24]2[CH2:25][CH2:26][CH:27]([C:29]([O:31][CH3:32])=[O:30])[O:28][C:23]=2[C:22]=1[CH2:35][CH2:36][CH3:37]>>[NH2:10][C:8]([C:7]1[CH:11]=[CH:12][C:13]([O:14][CH2:17][CH2:18][CH2:19][O:20][C:21]2[CH:34]=[CH:33][C:24]3[CH:25]=[CH:26][CH:27]([C:29]([O:31][CH3:32])=[O:30])[O:28][C:23]=3[C:22]=2[CH2:35][CH2:36][CH3:37])=[C:5]([CH2:4][CH:1]2[CH2:3][CH2:2]2)[C:6]=1[OH:15])=[O:9]

Komponenten

3

Edukt 2

HCID 14722828HCID 14722828, VerbindungHCID 15341843HCID 15341843, Verbindung

Produkt 1

HCID 22399592HCID 22399592, Verbindung

Versuchsvorschrift

The compound of Example 66 and the compound of Example 23 are reacted together under the conditions described in Example 24. The crude product is purified by chromatography on silica gel using ethyl acetate/hexane (4:6) as eluant to afford the product.

Aufarbeitung

  1. customThe crude product is purified by chromatography on silica gel
  2. customto afford the product

Quellen und Nachweise

ORD-Eintrag
ord-7eb969b88ebb49178a8446f4fbe2b04e
Quelldatensatz
uspto-grants-1994_05
Patentnummer
US05310951

Notizen zur Reaktion

Wird geladen…