Oxalic Acid → (+)-3-[4-[N-n-Propyl-N-(5-Methoxychroman-3-Yl)Amino]Butyl]-2,4-Dioxo-3-Azaspiro[4.5]Decane (Oxalate)

HRID 1034271Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1034271
[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH3:7][O:8][C:9]1[CH:18]=[CH:17][CH:16]=[C:15]2[C:10]=1[CH2:11][CH:12]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][N:24]1[C:28](=[O:29])[C:27]3([CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]3)[CH2:26][C:25]1=[O:35])[CH2:13][O:14]2.[C:36](O)(=O)[C:37](O)=O>>[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH2:1]([N:19]([CH2:20][CH2:21][CH2:22][CH2:23][N:24]1[C:28](=[O:29])[C:27]2([CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]2)[CH2:26][C:25]1=[O:35])[CH:12]1[CH2:11][C:10]2[C:15](=[CH:16][CH:17]=[CH:18][C:9]=2[O:8][CH3:7])[O:14][CH2:13]1)[CH2:36][CH3:37]

Komponenten

3

Edukt 2

HCID 971Oxalic AcidHCID 18966585(+)-3-{4-[N-(5-Methoxy-3-Chromanyl)Amino]Butyl}-2,4-Dioxo-3-Azaspiro[4.5]Decane Oxalate

Produkt 1

HCID 18966570(+)-3-[4-[N-n-Propyl-N-(5-Methoxychroman-3-Yl)Amino]Butyl]-2,4-Dioxo-3-Azaspiro[4.5]Decane (Oxalate)

Versuchsvorschrift

Using the procedure described in Example 10, but replacing the compound of Example 9 by the compound of Example 28, the product of the title is obtained. It is salified with oxalic acid.

Aufarbeitung

  1. customthe product of the title is obtained

Quellen und Nachweise

ORD-Eintrag
ord-c9f5b28761ff44259833019a90403507
Quelldatensatz
uspto-grants-1994_05
Patentnummer
US05314907

Notizen zur Reaktion

Wird geladen…