Allyl bromide → 3-allyl-5-methylthiazol-2(3H)-imine hydrobromide
Reaktionsgleichung
[NH2:1][C:2]1[S:3][C:4]([CH3:7])=[CH:5][N:6]=1.[CH2:8]([Br:11])[CH:9]=[CH2:10]>>[BrH:11].[CH2:10]([N:6]1[CH:5]=[C:4]([CH3:7])[S:3][C:2]1=[NH:1])[CH:9]=[CH2:8]Komponenten
3
Versuchsvorschrift
A mixture of 2-amino-5-methylthiazole (2.5 g) and allylbromide (3.31 g) was processed according to the method of Example 227A to afford the title compound that was taken directly to the next step. MS (ESI+) m/z 155 (M+H)+.
Quellen und Nachweise
- ORD-Eintrag
- ord-0246485785de45bfad61e1a05e53d620
- Quelldatensatz
- uspto-grants-2013_10
- Patentnummer
- US08546583B2
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