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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1038675Erstellt: 26. Oktober 2026

1,3-Dichloro-2-isocyanatobenzene → 1-(2,6-Dichloro-phenyl)-3-[6-(4-morpholin-4-yl-phenylamino)-pyrimidin-4-yl]-urea

https://huagongshe.com/reaction/1038675

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1,3-Dichloro-2-isocyanatobenzeneHCID 604537—
EduktN-(4-Morpholin-4-yl-phenyl)-pyrimidine-4,6-diamineHCID 66669896—
Produkt1-(2,6-Dichloro-phenyl)-3-[6-(4-morpholin-4-yl-phenylamino)-pyrimidin-4-yl]-ureaHCID 57710274—

Reaktionsschritte

The title compound is prepared analogously as described in Example 105B from N-(4-morpholin-4-yl-phenyl)-pyrimidine-4,6-diamine and 2,6-dichlorophenyl isocyanate. Faintly violet solid, HPLC: tR=3.74 min (purity: 100%, gradient F), ESI-MS: 459.3/461.3 [MH]+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08552002B2
Quelldatensatzuspto-grants-2013_10
ORD IDord-f908716032de4da69aa70d9be131131e
Quellennotizuspto-grants-2013_10