Benzene, 1-chloro-3-isocyanato- → 3-(3-Chloro-Phenyl)-1-[6-(4-fluoro-phenylamino)-pyrimidin-4-yl]-1-methyl-urea
Reaktionsgleichung
[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]2[CH:14]=[C:13]([NH:15][CH3:16])[N:12]=[CH:11][N:10]=2)=[CH:4][CH:3]=1.[Cl:17][C:18]1[CH:19]=[C:20]([N:24]=[C:25]=[O:26])[CH:21]=[CH:22][CH:23]=1>>[Cl:17][C:18]1[CH:19]=[C:20]([NH:24][C:25](=[O:26])[N:15]([C:13]2[CH:14]=[C:9]([NH:8][C:5]3[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=3)[N:10]=[CH:11][N:12]=2)[CH3:16])[CH:21]=[CH:22][CH:23]=1Komponenten
3
Versuchsvorschrift
The title compound is prepared analogously as described in Example 121 from N-(4-fluoro-phenyl)-N′-methyl-pyrimidine-4,6-diamine and 3-chlorophenyl isocyanate.
Quellen und Nachweise
- ORD-Eintrag
- ord-a29a2c15a000433aae1f3edd94090d0a
- Quelldatensatz
- uspto-grants-2013_10