HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isatoic Anhydride → 2-amino-N-(pyridin-2-yl)benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isatoic Anhydride | HCID 8359 | — |
| Edukt | 2-Aminopyridine | HCID 10439 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | 2-amino-N-(pyridin-2-yl)benzamide | HCID 276325 | 54% |
Reaktionsschritte
A mixture of isatoic anhydride 71 (8.7 g, 0.053 mol) and 2-aminopyridine (5 g, 0.06 mol) was heated in dioxane (30 mL) for 6-7 hours. After cooling, the solvent was evaporated in vacuo, the residue treated with water and recrystallized from EtOH/H2O to yield 72 (6 g, 54%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08552009B2 |
| Quelldatensatz | uspto-grants-2013_10 |
| ORD ID | ord-a4ba31314b7b40a2a3232c4beaa6d4cc |
| Quellennotiz | uspto-grants-2013_10 |