Ethyl Acetate → 1-Hydrazinothiocarbonylpiperidin-4-ol

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A solution of methyl hydrazinecarbothioate (1.0 g, 8.2 mmol) and piperidin-4-ol (1.24 g, 12.3 mmol) in ethanol (7 mL) was refluxed with heating at 90° C. for 2 days. After addition of ethyl acetate, the reaction solution was washed with saturated aqueous sodium chloride, dried over anhydrous magnesium sulfate and concentrated to give the crude desired product. The crude product was used directly for the next reaction.

Herkunft & Nachweise