Thionyl Chloride → 3-Nitro-5-(trifluoromethyl)benzoyl chloride
Reaktionsgleichung
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:12]=1)[C:7](O)=[O:8])([O-:3])=[O:2].S(Cl)([Cl:19])=O>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:12]=1)[C:7]([Cl:19])=[O:8])([O-:3])=[O:2]Komponenten
3
Versuchsvorschrift
A solution of thionyl chloride (30 ml) and 3-nitro-5-(trifluoromethyl)benzoic acid (10 g) was heated to reflux for 2 h. The reaction mixture was concentrated under reduced pressure and azeotroped with toluene (10 ml—removed under reduced pressure) to afford 3-nitro-5-(trifluoromethyl)benzoyl chloride.
Aufarbeitung
- temperatureto reflux for 2 h
- concentrationThe reaction mixture was concentrated under reduced pressure
- customazeotroped with toluene (10 ml—removed under reduced pressure)
Quellen und Nachweise
- ORD-Eintrag
- ord-8c96f968b55f49029bd9be4cd9d70eef
- Quelldatensatz
- uspto-grants-2013_10
- Patentnummer
- US08557996B2
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