Hexane → HCID 178516446, Verbindung

HRID 1042846Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1042846
CC1(C)O[C:6](=[O:8])[C:5](=[CH:9][NH:10][C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)C(=O)O1.CCCCCC>C1(OC2C=CC=CC=2)C=CC=CC=1>[N:10]1[C:11]2[C:12](=[CH:13][N:14]=[CH:15][CH:16]=2)[C:6]([OH:8])=[CH:5][CH:9]=1

Komponenten

4

Edukt 2

HCID 8058HexaneHCID 59427333HCID 59427333, Verbindung

Produkt 1

HCID 178516446HCID 178516446, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7583Diphenyl EtherLösungsmittel

Versuchsvorschrift

A solution of 2,2-dimethyl-5-((pyridin-4-ylamino)methylene)-1,3-dioxane-4,6-dione (1.149 g, 4.63 mmol) in diphenyl ether was heated at 200° C. for 20 min, then cooled to RT. Hexane was added and the mixture was stirred at RT for 30 mins. The solid was filtered off and washed with hexane to furnish 1,6-naphthyridin-4-ol as an off-brown solid.

Aufarbeitung

  1. filtrationThe solid was filtered off
  2. washwashed with hexane

Quellen und Nachweise

ORD-Eintrag
ord-953f7361ca1e44479d026f55ba6dd1e9
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08557816B2

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