Tetrahydrofuran → 4-Chlorobenzhydrol, (S)-

Beteiligte Stoffe

Reaktionsschritte

An operation was carried out in the same manner as in Example 14, except that 0.29 mL (0.375 mmol) of 4-chlorophenylmagnesium bromide (1.4 mol/L) prepared from magnesium and 4-chlorobenzene bromide was used instead of the anhydrous THF solution of phenylmagnesium bromide. Thus, (S)-4-chlorobenzhydrol was obtained. The conversion rate of the raw material was 96%, while the enantiomeric excess was 92% ee.

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