2-amino-4-fluoro-N-methoxybenzamide → HCID 58336569, Verbindung
Reaktionsgleichung
[CH3:1][N:2]1[C:6]([NH:7][C:8]2[CH:13]=[C:12](I)[C:11]([C:15]([F:18])([F:17])[F:16])=[CH:10][N:9]=2)=[CH:5][C:4]([CH3:19])=[N:3]1.[NH2:20][C:21]1[CH:31]=[C:30]([F:32])[CH:29]=[CH:28][C:22]=1[C:23]([NH:25][O:26][CH3:27])=[O:24]>>[CH3:1][N:2]1[C:6]([NH:7][C:8]2[CH:13]=[C:12]([NH:20][C:21]3[CH:31]=[C:30]([F:32])[CH:29]=[CH:28][C:22]=3[C:23]([NH:25][O:26][CH3:27])=[O:24])[C:11]([C:15]([F:18])([F:17])[F:16])=[CH:10][N:9]=2)=[CH:5][C:4]([CH3:19])=[N:3]1Komponenten
3
Versuchsvorschrift
This compound was prepared from N-(1,3-dimethylpyrazol-5-yl)-4-iodo-5-(trifluoromethyl)pyridin-2-amine and 2-amino-4-fluoro-N-methoxybenzamide. 81 mg, 48%; triturated in Et2O; NMR Spectrum: (DMSOd6) 2.08 (s, 3H), 3.55 (s, 3H), 3.70 (s, 3H), 6.04 (s, 1H), 6.74 (s, 1H), 6.97 (ddd, 1H), 7.43 (dd, 1H), 7.66 (dd, 1H), 8.28 (s, 1H), 9.07 (s, 1H), 10.04 (bs, 1H), 11.96 (bs, 1H); Mass spectrum: MH+ 439.
Aufarbeitung
- customtriturated in Et2O