HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Ethanol → Lamivudine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Ethanol | HCID 702 | — |
| Edukt | Lamivudine oxalate | HCID 86677229 | — |
| Lösungsmittel | Triethylamine | HCID 8471 | — |
| Produkt | Lamivudine | HCID 60825 | — |
Reaktionsschritte
Specifically, Lamivudine oxalate is added to ethanol, and an amount of triethylamine is added thereto at the temperature of 40˜45° C. for 0.5 hr, and stirred for 4 h at the same temperature. The mixture is centrifuged at room temperature, and a product is dried under vacuum at the temperature of 40˜45° C. to obtain Lamivudine crystal.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08569322B2 |
| Quelldatensatz | uspto-grants-2013_10 |
| ORD ID | ord-eb7e2ad85efd4d20b3416678baf39123 |
| Quellennotiz | uspto-grants-2013_10 |