Dimethylformamide dimethyl acetal → HCID 178484325, Verbindung

HRID 1047307Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1047307
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([NH2:10])=[O:9])=[N:6][CH:7]=1.CO[CH:13](OC)[N:14]([CH3:16])[CH3:15]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8](/[N:10]=[CH:13]/[N:14]([CH3:16])[CH3:15])=[O:9])=[N:6][CH:7]=1

Komponenten

3

Edukt 2

HCID 78373Dimethylformamide dimethyl acetalHCID 7351515-Bromopyridine-2-carboxamide

Produkt 1

HCID 178484325HCID 178484325, VerbindungAusbeute 95 %

Versuchsvorschrift

A solution of 5-bromopicolinamide (0.500 g, 2.49 mmol) and dimethylformamide dimethylacetal (20 mL), were heated to 85° C. for 3 h. The reaction was concentrated and the product was used directly in the next step (0.604 g, 95% yield). MS (ESI) m/z 257.1 [M+1]+.

Aufarbeitung

  1. concentrationThe reaction was concentrated

Quellen und Nachweise

ORD-Eintrag
ord-a2d91693cb2845b89e9a7654a5dea050
Quelldatensatz
uspto-grants-2013_10
Patentnummer
US08569494B2

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