Butyl 4-aminobenzoate → 4-[3-(Naphthalene-2-carbonyl)-thioureido]-benzoic acid butyl ester

Beteiligte Stoffe

Reaktionsschritte

2-Naphthoyl chloride (190 mg, 1 mmol) is added to a solution of ammonium thiocyanate (200 mg, about 3 mmol) in acetone (5 ml) and stirred at room temperature for 1 hour. Butyl 4-aminobenzoate (180 mg, 0.93 mmol) is added to the reaction mixture. Stirring is continued overnight at room temperature. The solid, which forms is filtered and washed with water (2×5 ml) followed by acetone/hexane (3:1) (2×10 ml) and dried.

Herkunft & Nachweise