Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate → Ethyl 4-[(5-methoxy-2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate	HCID 21262606	—
Edukt	6-amino-5-methoxy-1,3-benzothiazol-2(3H)-one	HCID 90014948	—
Produkt	Ethyl 4-[(5-methoxy-2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate	HCID 73442308	—

Reaktionsschritte

75 mg (332 μmol) ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS-No: 187725-00-4) were transformed in analogy to example 1 using 6-amino-5-methoxy-1,3-benzothiazol-2(3H)-one to give after working up and purification 20.0 mg (15%) of the title compound.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09382255B2
Quelldatensatz	uspto-grants-2016_07
ORD ID	ord-63520f616092494cb8a169fe16399d56
Quellennotiz	uspto-grants-2016_07