HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(Methylthio)phenyl isocyanate → 1-Cyclopentyl-7-methoxy-3-(3-methylsulfanyl-phenyl)-1H-pyrimido[5,4-c]quinoline-2,4-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(Methylthio)phenyl isocyanate | HCID 141418 | — |
| Edukt | 4-Cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester | HCID 67249718 | — |
| Produkt | 1-Cyclopentyl-7-methoxy-3-(3-methylsulfanyl-phenyl)-1H-pyrimido[5,4-c]quinoline-2,4-dione | HCID 44187610 | 64,6% |
Reaktionsschritte
1-Cyclopentyl-7-methoxy-3-(3-methylsulfanyl-phenyl)-1H-pyrimido[5,4-c]quinoline-2,4-dione (28 mg) was prepared from 4-cyclopentylamino-8-methoxy-quinoline-3-carboxylic acid ethyl ester (0.1 mmol) and 1-isocyanato-3-methylsulfanyl-benzene (0.5 mmol) following general procedure C. LCMS: m/z 434 [M+1]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09393245B2 |
| Quelldatensatz | uspto-grants-2016_07 |
| ORD ID | ord-d9432f2591314c0ea66b7bf4a236a6ea |
| Quellennotiz | uspto-grants-2016_07 |