Bupivacaine (USAN:INN:BAN) → Ephedrine
Reaktionsgleichung
[CH3:1]CCCN1C(C(NC2C(C)=CC=CC=2C)=O)CCCC1.[CH3:22][NH:23][CH2:24][C@H:25]([OH:34])[C:26]1[CH:27]=[CH:28][C:29](O)=[C:30](O)[CH:31]=1>>[CH3:1][C@H:24]([NH:23][CH3:22])[C@H:25]([OH:34])[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1Komponenten
3
Versuchsvorschrift
Microspheres containing bupivacaine loaded to about 75 percent by weight with bupivacaine are prepared, in a percent loading of about 0.05 percent, by weight, using the methods described in EXAMPLES 1-3 or EXAMPLES 4-9, above. In addition, microspheres containing added epinephrine, in a percent loadings of 0.001 percent, 0.05 percent and 1 percent, without bupivacaine, are also prepared according to EXAMPLES 1-3 or EXAMPLES 4-9, above.
Aufarbeitung
- customare prepared, in a percent loading of about 0.05 percent, by weight
- additionIn addition, microspheres containing