1,2-Dichlorobenzene → 4-(4-Fluorophenoxy)-2-(prop-2-en-1-yl)phenol
Reaktionsgleichung
C([O:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][C:12]2[CH:17]=[CH:16][C:15]([F:18])=[CH:14][CH:13]=2)=[CH:7][CH:6]=1)C=C.Cl[C:20]1[CH:25]=CC=C[C:21]=1Cl>>[F:18][C:15]1[CH:14]=[CH:13][C:12]([O:11][C:8]2[CH:7]=[CH:6][C:5]([OH:4])=[C:10]([CH2:25][CH:20]=[CH2:21])[CH:9]=2)=[CH:17][CH:16]=1Komponenten
3
Versuchsvorschrift
4-(4-fluorophenoxy)phenyl allyl ether (4.00 g, 16.37 mmol) was taken up in 1,2-dichlorobenzene (50 mL) and refluxed for 48 h. After cooling, the solvent was removed in vacuo and the resulting crude oil was chromatographed on silica gel (15% ethyl acetate/hexane) to afford the title compound.
Aufarbeitung
- temperaturerefluxed for 48 h
- temperatureAfter cooling
- customthe solvent was removed in vacuo
- customthe resulting crude oil was chromatographed on silica gel (15% ethyl acetate/hexane)