Methyl iodide → 4-bromo-1-methyl-1H-pyrrole-2-carbaldehyde
Reaktionsgleichung
[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[O:8])[NH:5][CH:6]=1.I[CH3:10]>>[CH3:10][N:5]1[CH:6]=[C:2]([Br:1])[CH:3]=[C:4]1[CH:7]=[O:8]Komponenten
3
Versuchsvorschrift
In a similar manner to Example 10(b), by reaction of 4 g (23 mmol) of 4-bromo-2-pyrrolecarboxaldehyde with 1.7 ml (27.6 mmol) of iodomethane, 2.3 g (50%) of the expected product are obtained, with a melting point of 123-4° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-f25dde047e9642c8a9daacad4c6a2426
- Quelldatensatz
- uspto-grants-2003_02
- Patentnummer
- US06515021B1
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