2-Chloro-4-[1-oxo-3-(3-hydroxyphenyl)propyl]benzoic acid → 2-Chloro-4-(1-hydroxy-3-(3-hydroxyphenyl)propyl)benzoic acid
Reaktionsgleichung
[Cl:1][C:2]1[CH:11]=[C:10]([CH:12]([OH:22])[CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([OH:21])[CH:16]=2)[CH:9]=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].ClC1C=C(C(=O)CCC2C=CC=C(O)C=2)C=CC=1C(O)=O>>[Cl:1][C:2]1[CH:11]=[C:10]([CH:12]([OH:22])[CH2:13][CH2:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([OH:21])[CH:16]=2)[CH:9]=[CH:8][C:3]=1[C:4]([OH:6])=[O:5]Komponenten
3
Versuchsvorschrift
This compound was prepared in 90% yield from rac.-2-chloro-4-[1-hydroxy-3-(3-hydroxyphenyl)propan-1-yl]benzoic acid, methyl ester (Example 94) by the procedure described for 2-chloro-4-[3-(3-hydroxyphenyl)-1-oxopropan-1-yl]benzoic acid (Example 95). The product was a racemic mixture and was not resolved.