Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Maleic Acid | HCID 444266 | — |
| Edukt | Enalapril | HCID 5388962 | — |
| Lösungsmittel | Acetonitrile | HCID 6342 | — |
| Produkt | Enalapril Maleate | HCID 5388961 | — |
Reaktionsschritte
N-(1(S)-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl-L-proline and acetonitrile are mixed and to this mixture is added maleic acid with heating at 70° C. and the mixture is gradually cooled to obtain N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanyl-L-proline maleate.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US06518436B2 |
|---|
| Quelldatensatz | uspto-grants-2003_02 |
|---|
| ORD ID | ord-1b7988bdc6d94551bb08879c7e77426e |
|---|
| Quellennotiz | uspto-grants-2003_02 |
|---|
