HCID 54513511, Verbindung → 4-Isopropyloxy-2-methylpyridine

HRID 1059869Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1059869
[CH:1]([O:4][C:5]1[CH:10]=[CH:9][N+:8]([O-])=[C:7]([CH3:12])[CH:6]=1)([CH3:3])[CH3:2]>CC(O)C.[Ni]>[CH:1]([O:4][C:5]1[CH:10]=[CH:9][N:8]=[C:7]([CH3:12])[CH:6]=1)([CH3:3])[CH3:2]

Komponenten

4

Edukt 1

HCID 54513511HCID 54513511, Verbindung

Produkt 1

HCID 186675734-Isopropyloxy-2-methylpyridineAusbeute 78,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 3776IsopropanolLösungsmittel

Versuchsvorschrift

A suspension of 4-isopropyloxy-2-methylpyridine N-oxide (0.78 g) in 2-propanol (10 ml) was hydrogenated over Raney-nickel (50% suspension in water, 1 ml) under a hydrogen atmosphere for 48 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 4-isopropyloxy-2-methylpyridine (555 mg).

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-5308d304416e473dab3b9bf7ec755edf
Quelldatensatz
uspto-grants-2003_02
Patentnummer
US06521643B1

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