4-(4-Methoxypyridin-2-yl)-2-nitrotoluene → 5-(4-Methoxypyridin-2-yl)-2-methylaniline

Beteiligte Stoffe

Reaktionsschritte

A suspension of 4-(4-methoxypyridin-2-yl)-2-nitrotoluene (300 mg) in tetrahydrofuran (3 ml) and ethanol (3 ml) was hydrogenated over palladium on carbon (10% w/w, 50% wet, 150 mg) under a hydrogen atmosphere for 3 hours. The catalyst was filtered off, and the filtrate was evaporated under reduced pressure to give 5-(4-methoxypyridin-2-yl)-2-methylaniline (254 mg).

Herkunft & Nachweise