Hydrogen Peroxide → N-Acetyl-D-Galactosamine

HRID 1060801

Reaktionsgleichung

Reaktionsgleichung von HRID 1060801
[CH3:1][C:2]([NH:4][CH:5]1[CH:10]([OH:11])[O:9][CH:8]([CH2:12][OH:13])[CH:7]([OH:14])[CH:6]1[OH:15])=[O:3].OO.[O:18]=[CH:19][C@@H:20]([C@H:22]([C@H:24]([C@@H:26]([CH2:28][OH:29])[OH:27])[OH:25])[OH:23])[OH:21]>>[C:2]([NH:4][C@@H:5]1[C@@H:6]([OH:15])[C@@H:7]([OH:14])[C@@H:8]([CH2:12][OH:13])[O:9][CH:10]1[OH:11])(=[O:3])[CH3:1].[O:18]=[CH:19][C@@H:20]([C@H:22]([C@H:24]([C@@H:26]([CH2:28][OH:29])[OH:27])[OH:25])[OH:23])[OH:21]

Komponenten

5

Edukt 3

HCID 784Hydrogen PeroxideHCID 899N-Acetyl-HexosamineHCID 3037556(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal

Produkt 2

HCID 35717N-Acetyl-D-GalactosamineHCID 3037556(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal

Versuchsvorschrift

N-Acetylhexosamine dialdose may, for example, be manufactured by oxidation of the 6-position of N-acetylhexosamine either chemically or enzymatically. An example of the chemical oxidation is a Fenton method where oxidation is carried out with hydrogen peroxide in the presence of a ferrous salt while that of the enzymatic oxidation is an oxidation using galactose oxidase [EC 1.1.3.9; Cooper, et al.; The Journal of Biological Chemistry, volume 234, pages 445-448 (1959)]. Oxidation of N-acetyl-D-galactosamine with galactose oxidase gives N-acetylgalactosamine dialdose.

Quellen und Nachweise

ORD-Eintrag
ord-d0252389814c410ab0ad4b9f25f57cfe
Quelldatensatz
uspto-grants-2003_02
Patentnummer
US06525082B1

Verknüpfte Notizen

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