4-chloro-3-nitro-N-(pyridin-3-ylmethyl)benzenesulfonamide → 4-Amino-3-nitro-N-(3-pyridinylmethyl)benzenesulfonamide

HRID 1061549Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1061549
Cl[C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][CH2:12][C:13]2[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=2)(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:19]([O-:21])=[O:20].[NH3:22].CO>>[NH2:22][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:11][CH2:12][C:13]2[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=2)(=[O:10])=[O:9])=[CH:4][C:3]=1[N+:19]([O-:21])=[O:20]

Komponenten

3

Edukt 2

HCID 28583054-chloro-3-nitro-N-(pyridin-3-ylmethyl)benzenesulfonamideHCID 21705897Ammonia methanol

Produkt 1

HCID 222851684-Amino-3-nitro-N-(3-pyridinylmethyl)benzenesulfonamide

Reaktionsbedingungen

Temperatur
100 °C

Versuchsvorschrift

Into a saturated ammonia-methanol solution (60 ml) was added 4-chloro-3-nitro-N-(pyridin-3-ylmethyl)benzenesulfonamide (2.77 g), followed by about 2 days of heating at 100° C. in a sealed tube. After the reaction, the solvent was evaporated under reduced pressure and the formed yellow crystals were collected by filtration and dried to obtain 4-amino-3-nitro-N-(pyridin-3-ylmethyl)benzenesulfonamide (2.51 g). Hereinafter, the compound of Reference Examples 26 was obtained similarly.

Aufarbeitung

  1. customAfter the reaction
  2. customthe solvent was evaporated under reduced pressure
  3. filtrationthe formed yellow crystals were collected by filtration
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-9f9472e3325a4e56940e70a7170ae712
Quelldatensatz
uspto-grants-2005_11
Patentnummer
US06960591B2

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