Thiophene-3-boronic acid → Tert-butyl 2-nitro-4-thien-3-ylphenylcarbamate

HRID 1061903

Reaktionsgleichung

Reaktionsgleichung von HRID 1061903
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].[S:19]1[CH:23]=[CH:22][C:21](B(O)O)=[CH:20]1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:21]2[CH:22]=[CH:23][S:19][CH:20]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

Komponenten

3

Edukt 2

HCID 581760Thiophene-3-boronic acidHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

Produkt 1

HCID 66865115Tert-butyl 2-nitro-4-thien-3-ylphenylcarbamate

Versuchsvorschrift

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and 3-thiopheneboronic acid according to the general procedure B. Obtained as a yellow solid (326 mg).

Quellen und Nachweise

ORD-Eintrag
ord-40cf452c91d140bf874ccae45b5c5401
Quelldatensatz
uspto-grants-2005_11
Patentnummer
US06960578B2

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