HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chlorophenylboronic acid → 5-Methyl-thiophene-2-carboxylic acid [7-(2-chloro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Chlorophenylboronic acid | HCID 2734322 | — |
| Edukt | 5-Methyl-thiophene-2-carboxylic acid (4-methoxy-7-iodo-benzothiazol-2-yl)-amide | HCID 86584906 | — |
| Produkt | 5-Methyl-thiophene-2-carboxylic acid [7-(2-chloro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide | HCID 86584907 | 80% |
Reaktionsschritte
5-Methyl-thiophene-2-carboxylic acid [7-(2-chloro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide is synthesized from 5-methyl-thiophene-2-carboxylic acid (7-iodo-4-methoxy-benzothiazol-2-yl)-amide (100 mg, 0.23 mmol) and 2-chlorophenylboronic acid (54 mg, 0.35 mmol) using the general procedure A as a light yellow solid in 80% yield. MS: m/e=415 (M+H+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06963000B2 |
| Quelldatensatz | uspto-grants-2005_11 |
| ORD ID | ord-f9c666cec02742aa8fb33579d961c4a7 |
| Quellennotiz | uspto-grants-2005_11 |