HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Nitrophenylboronic Acid → 5-Methyl-thiophene-2-carboxylic acid [7-(3-nitro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Nitrophenylboronic Acid | HCID 1677 | — |
| Edukt | 5-Methyl-thiophene-2-carboxylic acid (4-methoxy-7-iodo-benzothiazol-2-yl)-amide | HCID 86584906 | — |
| Produkt | 5-Methyl-thiophene-2-carboxylic acid [7-(3-nitro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide | HCID 86584908 | 42% |
Reaktionsschritte
5-Methyl-thiophene-2-carboxylic acid [7-(3-nitro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide is synthesized from 5-methyl-thiophene-2-carboxylic acid (7-iodo-4-methoxy-benzothiazol-2-yl)-amide (155 mg, 0.36 mmol) and 3-nitrophenylboronic acid (135 mg, 0.81 mmol) using the general procedure A as a light yellow crystalls in 42% yield. MS: m/e=425 (M+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06963000B2 |
| Quelldatensatz | uspto-grants-2005_11 |
| ORD ID | ord-347ea0ca33ac413283ada8ae74d85d0a |
| Quellennotiz | uspto-grants-2005_11 |