(7-Mercapto-indan-4-yloxy)-acetic Acid Methyl Ester → {7-[5-(4-Trifluoromethyl-phenyl)-isoxazol-3-ylmethylsulfanyl]-indan-4-yloxy}-acetic acid
Reaktionsgleichung
Cl[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=2)[O:5][N:4]=1.C[O:19][C:20](=[O:33])[CH2:21][O:22][C:23]1[CH:31]=[CH:30][C:29]([SH:32])=[C:28]2[C:24]=1[CH2:25][CH2:26][CH2:27]2>>[F:15][C:14]([F:17])([F:16])[C:11]1[CH:12]=[CH:13][C:8]([C:6]2[O:5][N:4]=[C:3]([CH2:2][S:32][C:29]3[CH:30]=[CH:31][C:23]([O:22][CH2:21][C:20]([OH:33])=[O:19])=[C:24]4[C:28]=3[CH2:27][CH2:26][CH2:25]4)[CH:7]=2)=[CH:9][CH:10]=1Komponenten
3
Versuchsvorschrift
The title compound was prepared in a manner analogous to Example 1F using 42C and 12C. MS m/z 464 (M+1).
Quellen und Nachweise
- ORD-Eintrag
- ord-65fed0704b3342b68c04984bb64a1f7c
- Quelldatensatz
- uspto-grants-2005_11