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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1066011Erstellt: 27. Oktober 2026

Hydrochloric Acid → 2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, hydrochloride, (S)-

https://huagongshe.com/reaction/1066011

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktHydrochloric AcidHCID 313—
EduktTimololHCID 33624—
LösungsmittelIsopropanolHCID 3776—
Produkt2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, hydrochloride, (S)-HCID 15520891%

Reaktionsschritte

0.8 ml of a 7M HCl solution in isopropanol was added dropwise to a magnetically stirred solution of timolol (1.4 g) in isopropanol (30 ml). The solution was stirred for 30 minutes. The reaction mixture was freed of the solvent at reduced pressure. 1.47 g of pure product was obtained (yield 91%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06242432B1
Quelldatensatzuspto-grants-2001_06
ORD IDord-4441b34afb6240a7bee27d9b58d30fb9
Quellennotizuspto-grants-2001_06