Ammonium dithiocarbamate → Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetate

HRID 1067404

Reaktionsgleichung

Reaktionsgleichung von HRID 1067404
[CH2:1]([O:3][C:4](=[O:19])[CH2:5][O:6][C:7]1[C:16]2[CH2:15][CH2:14][CH2:13][C:12](=O)[C:11]=2[CH:10]=[CH:9][C:8]=1Br)[CH3:2].[C:20](=[S:23])([S-:22])[NH2:21].[NH4+]>C(O)C>[CH2:1]([O:3][C:4](=[O:19])[CH2:5][O:6][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:16]=1[CH2:15][CH2:14][C:13]1[S:22][C:20]([SH:23])=[N:21][C:12]=12)[CH3:2]

Komponenten

4

Edukt 2

HCID 11083854Ammonium dithiocarbamateHCID 21193671Ethyl [(2-bromo-5,6,7,8-tetrahydro-5-oxo-1-naphthalenyl)oxy]acetate

Produkt 1

HCID 178472952Ethyl[(2-mercapto-4,5-dihydronaphtho[1,2-d]thiazol-6-yl)oxy)acetateAusbeute 76 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of ethyl[(2-bromo-5,6,7,8-tetrahydro-5-oxo-1-naphthalenyl)oxy]acetate (2.63 g, 8.04 mmol), ammonium dithiocarbamate (1.06 g, 9.60 mmol), and ethanol (30 mL) was refluxed for 14 hours. After cooling, the solid precipitate was recovered by filtration to provide 1.96 g of the title compound. Amorphous solid. Yield 76%.

Aufarbeitung

  1. temperaturewas refluxed for 14 hours
  2. temperatureAfter cooling
  3. filtrationthe solid precipitate was recovered by filtration

Quellen und Nachweise

ORD-Eintrag
ord-6f5f3deb684e4dc4b6e97db8d01c6841
Quelldatensatz
uspto-grants-2001_06
Patentnummer
US06248766B1

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