2-Aminopyrimidine-5-boronic acid, pinacol ester → 1-(4-((2-(2-Aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one
Reaktionsgleichung
[CH3:30][C:31]1([CH3:32])[C:33]([CH3:34])([CH3:35])[O:36][B:37]([c:38]2[cH:39][n:40][c:41]([NH2:44])[n:42][cH:43]2)[O:45]1.[Cl:1][c:2]1[n:3][c:4]([N:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[c:5]2[c:6]([n:7]1)[c:8]([CH3:23])[c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:18]([CH:19]([CH3:20])[OH:21])=[O:22])[CH2:16][CH2:17]1)[s:10]2>>[c:2]1(-[c:38]2[cH:39][n:40][c:41]([NH2:44])[n:42][cH:43]2)[n:3][c:4]([N:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[c:5]2[c:6]([n:7]1)[c:8]([CH3:23])[c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:18]([CH:19]([CH3:20])[OH:21])=[O:22])[CH2:16][CH2:17]1)[s:10]2Komponenten
3
Edukt 2
Produkt 1
Quellen und Nachweise
- ORD-Eintrag
- ord-fe35b4c4e3ce427f8e836f2a6325d9ae
- Quelldatensatz
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)