Cyanuric chloride → 4,6-Dichloro-N,N-dihexyl-1,3,5-triazin-2-amine

Beteiligte Stoffe

Reaktionsschritte

Dihexylamine (6.3 mL, 27 mmol) was added to a mixture of cyanuric chloride (5 0 g, 27 mmol) and sodium carbonate (2.9 g, 27 mmol) in acetonitrile (50 mL). The reaction mixture was heated to reflux for 16 h and then allowed to col to ambient temperature. The mixture was diluted with ethyl acetate and water. The phases were separated and the organic phase was washed with brine, dried over magnesium sulfate, and concentrated under reduced pressure. The crude material was purified by flash column chromatography through silica get (elution with 3:1 hexanes:chloroform) to afford 2,4-dichloro-6-dihexylamino-1,3,5-triazine.

Herkunft & Nachweise