Isobutyryl chloride → 6,7-Dimethoxy-2-isobutyrylnaphthalene

HRID 1070668Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1070668
[CH3:1][O:2][C:3]1[C:12]([O:13][CH3:14])=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=1.[C:15](Cl)(=[O:19])[CH:16]([CH3:18])[CH3:17].[Cl-].[Al+3].[Cl-].[Cl-]>C(Cl)Cl>[CH3:14][O:13][C:12]1[CH:11]=[C:10]2[C:5](=[CH:4][C:3]=1[O:2][CH3:1])[CH:6]=[C:7]([C:15](=[O:19])[CH:16]([CH3:18])[CH3:17])[CH:8]=[CH:9]2

Komponenten

5

Edukt 3

HCID 62325Isobutyryl chlorideHCID 6047082,3-DimethoxynaphthaleneHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 114142376,7-Dimethoxy-2-isobutyrylnaphthalene

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

The solution of 2,3-dimethoxynaphthalene (16.5 g ), isobutyroylchloride (12.5 g) and aluminum chloride (15.7 g) in methylene chloride (200 ml) was stirred at ambient temperature overnight. The solution was then washed with saturated sodium bicarbonate and water, dried with sodium sulfate and evaporated. Finally the crude product was triturated with ether. Yield: 13.5 g, melting point 103-105° C.

Aufarbeitung

  1. washThe solution was then washed with saturated sodium bicarbonate and water
  2. dry with materialdried with sodium sulfate
  3. customevaporated
  4. customFinally the crude product was triturated with ether

Quellen und Nachweise

ORD-Eintrag
ord-73fdc15dc46c40ffafb067fddaaf97bf
Quelldatensatz
uspto-grants-2005_06
Patentnummer
US06903114B2

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