Piperidine → 4-Piperidinylbut-1-ene

HRID 1072041

Reaktionsgleichung

Reaktionsgleichung von HRID 1072041
Br[CH2:2][CH2:3][CH:4]=[CH2:5].[NH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1>>[N:6]1([CH2:7][CH2:8][CH:9]=[CH2:10])[CH2:11][CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

3

Edukt 2

HCID 8082PiperidineHCID 21241Homoallyl bromide

Produkt 1

HCID 45622824-Piperidinylbut-1-eneAusbeute 93,4 %

Versuchsvorschrift

4-Bromobut-1-ene (1.35 g) was treated with piperidine (1.7 g) and heated at reflux for 3 hours. The mixture was cooled to ambient temperature, filtered and the residue washed with ether (50 mL). The combined filtrate and washings were evaporated to give the title compound (1.3 g).

Aufarbeitung

  1. temperatureheated
  2. temperatureat reflux for 3 hours
  3. filtrationfiltered
  4. washthe residue washed with ether (50 mL)
  5. customThe combined filtrate and washings were evaporated

Quellen und Nachweise

ORD-Eintrag
ord-2abbff9c572e4f08a048bf11c5ba08aa
Quelldatensatz
uspto-grants-2005_06
Patentnummer
US06908929B2

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